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Steven Laureys

Head, Coma Science Group, Cyclotron Research Centre and Neurology Dept

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Yuval Nir
Postdoctoral fellow, University of Wisconsin-Madison

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Latest Publications

Visual fixation in the vegetative state: an observational case series PET study.
Bruno MA, Vanhaudenhuyse A, Schnakers C, Boly M, Gosseries O, Demertzi A, Majerus S, Moonen G, Hustinx R, Laureys S
Transcranial magnetic stimulation in disorders of consciousness.
Lapitska N, Gosseries O, Delvaux V, Overgaard M, Nielsen F, Maertens de noordhout A, Moonen G, Laureys S
Contribution of functional neuroimaging studies to the understanding of the mechanisms of general anesthesia
Boveroux P, Bonhomme V, Kirsch M, Noirhomme Q, Ledoux D, Hans G, Laureys S, Luxen A, Brichant JF

About

Research

Our team assesses the recovery of neurological disability and of neuronal plasticity in severely brain damaged patients with altered states of consciousness by means of multimodal functional neuroimaging It aims at characterizing the brain structure and the residual cerebral function in patients who survive a severe brain injury: patients in coma, vegetative state, minimally conscious state and locked in syndrome.

The importance of this project is twofold. First, these patients represent a problem in terms of diagnosis, prognosis, treatment and daily management. Second, these patients offer the opportunity to explore human consciousness, which is presently one major conundrum neurosciences have to solve. Indeed, these patients present a complete, nearly graded, range of conscious states from unconsciousness (coma) to full awareness (locked-in syndrome).

Our research confronts clinical expertise and bedside behavioral evaluation of altered states of consciousness with state-of-the-art multimodal imaging combining the information from positron emission tomography (PET), functional magnetic resonance imaging (fMRI), structural MRI, electroencephalography (EEG) and event related potential (ERP) data.

Background

MD, PhD, leads the Coma Science Group at the Cyclotron Research Center and Department of Neurology, Sart Tilman Liège University Hospital.

Clinical Professor (ULg) and Senior Research Associate (tenure) at the Belgian National Fund of Scientific Research (FNRS). He graduated as a Medical Doctor from the Vrije Universiteit Brussel Belgium, in 1993. While specializing in Neurology he entered a research career and obtained his M.Sc. in Pharmaceutical Medicine working on pain and stroke using in vivomicrodialysis and diffusion MRI in the rat (1997). Drawn by functional neuroimaging, he moved to the Cyclotron Research Center at the University of Liège, Belgium, where he obtained his Ph.D. (2000) and his "thèse d'agrégation de l'enseignement supérieur" (2007) studying residual brain function in coma, vegetative, minimally conscious and locked-in states .

He is board-certified in neurology (1998) and in palliative and end-of-life medicine (2004) and presently is invited professor at the Collège Belgique (Belgian Royal Academy of Sciences) and chair of the "European Neurological Society Subcommittee on Coma and disorders of consciousness".

A recipient of the William James Prize (2004) from the Association for the Scientific Study of Consciousness (ASSC) and the Cognitive Neuroscience Society (CNS) Young Investigator Award (2007), he published several books: The Neurology of Consciousness (with Giulio Tononi, Academic Press,2008); Coma Science (with Adrian Owen et Nicholas Schiff; Elsevier 2009); Disorders of Consciousness (with Nicholas Schiff, Wiley, 2009) and The Boundaries of Consciousness (Elsevier, 2005).

He is a member of the American Academy of Neurology Committee for the Development of Practice Guidelines for the Vegetative and Minimally Conscious State (2007) (Robert G. Holloway, Dan Larriviere, Michael A. Williams), is Honorary International Fellow of the Royal Hospital of Neuro-disability, London, UK (Keith Andrews) and was invited member of the 2004 Congress on Life-Sustaining Treatments in the Vegetative State organized by the Vatican’s Pontifical Academy of Life (Gian Luigi Gigli) and the 2006 Mohonk Consensus Meeting for the US Congressional Report on Disorders of Consciousness (Joseph Giacino).